Convenient synthesis of 3,4-dichloro-5-hydroxy-2(5H)-furanone glycoconjugates.
نویسندگان
چکیده
3,4-Dichloro-5-hydroxy-2(5H)-furanone treated with methyl chloroformate in the presence of diisopropylethylamine (Hünig's base) gave the corresponding carbonate. The labile methoxycarbonyloxy group smoothly undergoes substitution by amino alcohols. The obtained 5-(w-hydroxyalkylamino) mucochloric acid derivatives reacted with peracetylated glucals using triphenylphosphine hydrobromide as a catalyst to give the title muchloric acid glycoconjugates.
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ورودعنوان ژورنال:
- Molecules
دوره 16 2 شماره
صفحات -
تاریخ انتشار 2011